Cross Modulation between the Androgen Receptor Axis and Protocadherin-PC in Mediating Neuroendocrine Transdifferentiation and Therapeutic Resistance of Prostate Cancer
Castration-resistant prostate cancers (CRPCs) that relapse after androgen deprivation therapies (ADTs) are responsible for the majority of mortalities from prostate cancer (PCa). While mechanisms enabling recurrent activity of androgen receptor (AR) are certainly involved in the development of CRPC...
Main Authors: | Stéphane Terry, Pascale Maillé, Habiba Baaddi, Laurence Kheuang, Pascale Soyeux, Nathalie Nicolaiew, Jocelyn Ceraline, Virginie Firlej, Himisha Beltran, Yves Allory, Alexandre de la Taille, Francis Vacherot |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-07-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S147655861380070X |
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