Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trial

Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trial

Abstract Background Severe malaria is a medical emergency associated with high mortality. Adequate treatment requires initial parenteral therapy for fast parasite clearance followed by longer acting oral antimalarial drugs for cure and prevention of recrudescence. Methods In a randomized controlled...

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Bibliographic Details
Main Authors: Pauline Byakika-Kibwika, Jane Achan, Mohammed Lamorde, Carine Karera-Gonahasa, Agnes N. Kiragga, Harriet Mayanja-Kizza, Noah Kiwanuka, Sam Nsobya, Ambrose O. Talisuna, Concepta Merry
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Infectious Diseases
Subjects:
Artesunate
Quinine
Artemisinin combination therapy
Severe malaria
Re-infection
Online Access:http://link.springer.com/article/10.1186/s12879-017-2924-5

Internet

http://link.springer.com/article/10.1186/s12879-017-2924-5

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