Y-Box Binding Protein-1 Promotes Epithelial-Mesenchymal Transition in Sorafenib-Resistant Hepatocellular Carcinoma Cells

Y-Box Binding Protein-1 Promotes Epithelial-Mesenchymal Transition in Sorafenib-Resistant Hepatocellular Carcinoma Cells

Hepatocellular carcinoma is one of the most common cancer types worldwide. In cases of advanced-stage disease, sorafenib is considered the treatment of choice. However, resistance to sorafenib remains a major obstacle for effective clinical application. Based on integrated phosphoproteomic and The C...

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Bibliographic Details
Main Authors: Li-Zhu Liao, Chih-Ta Chen, Nien-Chen Li, Liang-Chun Lin, Bo-Shih Huang, Ya-Hui Chang, Lu-Ping Chow
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocellular carcinoma cell
drug resistance
sorafenib
YB-1
S102 phosphorylation
epithelial-mesenchymal transition
Online Access:https://www.mdpi.com/1422-0067/22/1/224

Internet

https://www.mdpi.com/1422-0067/22/1/224

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