Selenium preserves mitochondrial function, stimulates mitochondrial biogenesis, and reduces infarct volume after focal cerebral ischemia

Selenium preserves mitochondrial function, stimulates mitochondrial biogenesis, and reduces infarct volume after focal cerebral ischemia

<p>Abstract</p> <p>Background</p> <p>Mitochondrial dysfunction is one of the major events responsible for activation of neuronal cell death pathways during cerebral ischemia. Trace element selenium has been shown to protect neurons in various diseases conditions. Presen...

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Bibliographic Details
Main Authors: Mehta Suresh L, Kumari Santosh, Mendelev Natalia, Li P
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Neuroscience
Subjects:
Cerebral ischemia
Glutamate
Hypoxia
Mitochondrial biogenesis
Respiratory complexes
Selenium
Online Access:http://www.biomedcentral.com/1471-2202/13/79

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http://www.biomedcentral.com/1471-2202/13/79

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