A Novel Peptide Binding Prediction Approach for HLA-DR Molecule Based on Sequence and Structural Information

MHC molecule plays a key role in immunology, and the molecule binding reaction with peptide is an important prerequisite for T cell immunity induced. MHC II molecules do not have conserved residues, so they appear as open grooves. As a consequence, this will increase the difficulty in predicting MHC...

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Bibliographic Details
Main Authors: Zhao Li, Yilei Zhao, Gaofeng Pan, Jijun Tang, Fei Guo
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/3832176