TLGP: a flexible transfer learning algorithm for gene prioritization based on heterogeneous source domain

TLGP: a flexible transfer learning algorithm for gene prioritization based on heterogeneous source domain

Abstract Background Gene prioritization (gene ranking) aims to obtain the centrality of genes, which is critical for cancer diagnosis and therapy since keys genes correspond to the biomarkers or targets of drugs. Great efforts have been devoted to the gene ranking problem by exploring the similarity...

Full description

Bibliographic Details
Main Authors: Yan Wang, Zuheng Xia, Jingjing Deng, Xianghua Xie, Maoguo Gong, Xiaoke Ma
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Bioinformatics
Subjects:
Gene prioritizatio
Transfer learning
Gene co-expression network
Integrative analysis
Online Access:https://doi.org/10.1186/s12859-021-04190-9

Internet

https://doi.org/10.1186/s12859-021-04190-9

Similar Items