Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response

Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response

The RecA protein orchestrates the cellular response to DNA damage via its multiple roles in the bacterial SOS response. Lack of tools that provide unambiguous access to the various RecA states within the cell have prevented understanding of the spatial and temporal changes in RecA structure/function...

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Bibliographic Details
Main Authors: Harshad Ghodke, Bishnu P Paudel, Jacob S Lewis, Slobodan Jergic, Kamya Gopal, Zachary J Romero, Elizabeth A Wood, Roger Woodgate, Michael M Cox, Antoine M van Oijen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-02-01
Series:eLife
Subjects:
SOS response
RecA
DNA damage
DNA repair intermediates
live cell imaging
single molecule imaging
Online Access:https://elifesciences.org/articles/42761

Internet

https://elifesciences.org/articles/42761

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