Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters

Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters

The extracellular matrix (ECM) is a major component of tumors and a significant contributor to cancer progression. In this study, we use proteomics to investigate the ECM of human mammary carcinoma xenografts and show that primary tumors of differing metastatic potential differ in ECM composition. B...

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Bibliographic Details
Main Authors: Alexandra Naba, Karl R Clauser, John M Lamar, Steven A Carr, Richard O Hynes
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-03-01
Series:eLife
Subjects:
extracellular matrix
tumor microenvironment
proteomics
breast cancer
metastasis
tumor stroma
Online Access:https://elifesciences.org/articles/01308

Internet

https://elifesciences.org/articles/01308

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