DNA methylation and miRNA-1296 act in concert to mediate spatiotemporal expression of KPNA7 during bovine oocyte and early embryonic development

DNA methylation and miRNA-1296 act in concert to mediate spatiotemporal expression of KPNA7 during bovine oocyte and early embryonic development

Abstract Background Epigenetic regulation of oocyte-specific maternal factors is essential for oocyte and early embryonic development. KPNA7 is an oocyte-specific maternal factor, which controls transportation of nuclear proteins important for early embryonic development. To elucidate the epigenetic...

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Bibliographic Details
Main Authors: Lei Wang, Jacqelyn M. Hand, Liyuan Fu, George W. Smith, Jianbo Yao
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Developmental Biology
Subjects:
DNA methylation
miRNA
Oocyte
Early embryonic development
Maternal
Cattle
Online Access:https://doi.org/10.1186/s12861-019-0204-x

Internet

https://doi.org/10.1186/s12861-019-0204-x

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