Efficacy and acquired resistance for EGFR-TKI plus thoracic SBRT in patients with advanced EGFR-mutant non–small-cell lung cancer: a propensity-matched retrospective study

Efficacy and acquired resistance for EGFR-TKI plus thoracic SBRT in patients with advanced EGFR-mutant non–small-cell lung cancer: a propensity-matched retrospective study

Abstract Background This retrospective study aimed to evaluate the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) with stereotactic body radiation therapy (SBRT) and to elucidate potential mechanisms of acquired resistance. Methods Patients with advanced NSCLC...

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Bibliographic Details
Main Authors: Xia Wang, Zhimin Zeng, Jing Cai, Peng Xu, Pingan Liang, Yuxi Luo, Anwen Liu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Non-small-cell lung cancer
Epidermal growth factor receptor tyrosine kinase inhibitors
Stereotactic body radiation therapy
Propensity score matching
Acquired resistance mechanism
Online Access:https://doi.org/10.1186/s12885-021-08228-2

Internet

https://doi.org/10.1186/s12885-021-08228-2

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