Glucose-regulated protein 78 binds to and regulates the melanocortin-4 receptor

Metabolic disease: Apprehending an appetite adjuster A molecular ‘chaperone’ helps regulate an essential metabolic signaling protein by ensuring that the protein is in the right place at the right time. The melanocortin-4 receptor (MC4R) controls food intake and energy burning. Abnormal MC4R activit...

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Bibliographic Details
Main Authors: Ye Ran Yoon, Tae-Gul Lee, Mi-Hyun Choi, Seung Woo Shin, Young-Gyu Ko, Im Joo Rhyu, Dong-Hoon Kim, Je Kyung Seong, Ja-Hyun Baik
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0144-8