Interferon Regulatory Factor 9 Promotes Lung Cancer Progression via Regulation of Versican

Interferon Regulatory Factor 9 Promotes Lung Cancer Progression via Regulation of Versican

Transcription factors can serve as links between tumor microenvironment signaling and oncogenesis. Interferon regulatory factor 9 (IRF9) is recruited and expressed upon interferon stimulation and is dependent on cofactors that exert in tumor-suppressing or oncogenic functions via the JAK-STAT pathwa...

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Bibliographic Details
Main Authors: David Brunn, Kati Turkowski, Stefan Günther, Andreas Weigert, Thomas Muley, Mark Kriegsmann, Hauke Winter, Reinhard H. Dammann, Georgios T. Stathopoulos, Michael Thomas, Andreas Guenther, Friedrich Grimminger, Soni S. Pullamsetti, Werner Seeger, Rajkumar Savai
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
lung cancer
adenocarcinoma
tumor microenvironment (TME)
type I interferons (IFNs)
interferon regulatory factor 9 (IRF9)
versican (VCAN)
Online Access:https://www.mdpi.com/2072-6694/13/2/208

Internet

https://www.mdpi.com/2072-6694/13/2/208

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