Somatic Copy Number Alterations in Human Cancers: An Analysis of Publicly Available Data From The Cancer Genome Atlas

Somatic Copy Number Alterations in Human Cancers: An Analysis of Publicly Available Data From The Cancer Genome Atlas

Somatic copy number alterations (SCNAs) are a pervasive trait of human cancers that contributes to tumorigenesis by affecting the dosage of multiple genes at the same time. In the past decade, The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) initiatives have gener...

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Bibliographic Details
Main Authors: Luuk Harbers, Federico Agostini, Marcin Nicos, Dimitri Poddighe, Magda Bienko, Nicola Crosetto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
copy number alterations
cancer
TCGA
cosmic genes
3D genome
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.700568/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.700568/full

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