Engineering a vector-based pan-Leishmania vaccine for humans: proof of principle

Abstract Leishmaniasis is a spectrum of diseases transmitted by sand fly vectors that deposit Leishmania spp. parasites in the host skin during blood feeding. Currently, available treatment options are limited, associated with high toxicity and emerging resistance. Even though a vaccine for human le...

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Bibliographic Details
Main Authors: Pedro Cecílio, James Oristian, Claudio Meneses, Tiago D. Serafim, Jesus G. Valenzuela, Anabela Cordeiro da Silva, Fabiano Oliveira
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-75410-0