Prior Antibiotic Therapy and the Onset of Healthcare-Associated Infections Sustained by Multidrug-Resistant <i>Klebsiella pneumoniae</i> in Intensive Care Unit Patients: A Nested Case–Control Study

Prior Antibiotic Therapy and the Onset of Healthcare-Associated Infections Sustained by Multidrug-Resistant <i>Klebsiella pneumoniae</i> in Intensive Care Unit Patients: A Nested Case–Control Study

Epidemiological research has demonstrated direct relationships between antibiotic consumption and the emergence of multidrug-resistant (MDR) bacteria. In this nested case–control study, we assessed whether prior exposure to antibiotic therapy and its duration affect the onset of healthcare-associate...

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Bibliographic Details
Main Authors: Giuseppe Migliara, Valentina Baccolini, Claudia Isonne, Sara Cianfanelli, Carolina Di Paolo, Annamaria Mele, Lorenza Lia, Angelo Nardi, Carla Salerno, Susanna Caminada, Vittoria Cammalleri, Francesco Alessandri, Guglielmo Tellan, Giancarlo Ceccarelli, Mario Venditti, Francesco Pugliese, Carolina Marzuillo, Corrado De Vito, Maria De Giusti, Paolo Villari
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antibiotics
Subjects:
healthcare-associated infections
antibiotic exposure
intensive care unit
multidrug resistance
<i>Klebsiella pneumoniae</i>
Online Access:https://www.mdpi.com/2079-6382/10/3/302

Internet

https://www.mdpi.com/2079-6382/10/3/302

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