Junín virus infection of human hematopoietic progenitors impairs in vitro proplatelet formation and platelet release via a bystander effect involving type I IFN signaling.

Junín virus infection of human hematopoietic progenitors impairs in vitro proplatelet formation and platelet release via a bystander effect involving type I IFN signaling.

Argentine hemorrhagic fever (AHF) is an endemo-epidemic disease caused by Junín virus (JUNV), a member of the arenaviridae family. Although a recently introduced live attenuated vaccine has proven to be effective, AHF remains a potentially lethal infection. Like in other viral hemorrhagic fevers (VH...

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Bibliographic Details
Main Authors: Roberto G Pozner, Agustín E Ure, Carolina Jaquenod de Giusti, Lina P D'Atri, Joseph E Italiano, Oscar Torres, Victor Romanowski, Mirta Schattner, Ricardo M Gómez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2855331?pdf=render

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http://europepmc.org/articles/PMC2855331?pdf=render

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