Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

Embryonic stem cells (ESCs) are cell lines derived from the mammalian pre-implantation embryo. Here we assess the impact of derivation and culture conditions on both functional potency and ESC transcriptional identity. Individual ESCs cultured in either two small-molecule inhibitors (2i) or with kno...

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Bibliographic Details
Main Authors: Javier Martin Gonzalez, Sophie M. Morgani, Robert A. Bone, Kasper Bonderup, Sahar Abelchian, Cord Brakebusch, Joshua M. Brickman
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116301333

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http://www.sciencedirect.com/science/article/pii/S2213671116301333

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