LKB1 suppresses androgen synthesis in a mouse model of hyperandrogenism via IGF‐1 signaling

Polycystic ovary syndrome (PCOS) is a major cause of anovulatory sterility in women, and most PCOS patients exhibit hyperandrogenism (HA). Liver kinase b1 (LKB1) is a tumor suppressor that has recently been reported to be involved in PCOS. However, the mechanism by which LKB1 affects HA has not prev...

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Bibliographic Details
Main Authors: Ying Xu, Yongxing Gao, Zufang Huang, Yan Zheng, Wenjuan Teng, Deyan Zheng, Xiaohua Zheng
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12723