PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer
Abstract Background Previous studies revealed somatic mutations of the cationic trypsinogen gene (PRSS1) in patients with chronic pancreatitis and pancreatic cancer. However, whether PRSS1 mutations trigger pancreatic cancer and/or promote malignant proliferation and metastasis in pancreatic cancer...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-09-01
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Series: | Molecular Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s10020-019-0111-4 |