Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults

Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults

Age-related episodic memory decline is characterized by striking heterogeneity across individuals. Hippocampal pattern completion is a fundamental process supporting episodic memory. Yet, the degree to which this mechanism is impaired with age, and contributes to variability in episodic memory, rema...

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Bibliographic Details
Main Authors: Alexandra N Trelle, Valerie A Carr, Scott A Guerin, Monica K Thieu, Manasi Jayakumar, Wanjia Guo, Ayesha Nadiadwala, Nicole K Corso, Madison P Hunt, Celia P Litovsky, Natalie J Tanner, Gayle K Deutsch, Jeffrey D Bernstein, Marc B Harrison, Anna M Khazenzon, Jiefeng Jiang, Sharon J Sha, Carolyn A Fredericks, Brian K Rutt, Elizabeth C Mormino, Geoffrey A Kerchner, Anthony D Wagner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
episodic memory
aging
hippocampus
cortical reinstatement
pattern completion
functional magnetic resonance imaging
Online Access:https://elifesciences.org/articles/55335

Internet

https://elifesciences.org/articles/55335

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