Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone

Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone

Abstract Recently, the Clinical Pharmacogenetics Implementation Consortium (CPIC) have revised recommendations for the translation of CYP2D6 genotype to phenotype. Changes affect phenotype grouping, as well as the value used to calculate activity score for the CYP2D6*10 allele to better reflect the...

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Bibliographic Details
Main Authors: Yaowaluck Hongkaew, Andrea Gaedigk, Bob Wilffert, Nattawat Ngamsamut, Wiranpat Kittitharaphan, Penkhae Limsila, Chonlaphat Sukasem
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83570-w

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