Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells

Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells

<p>Abstract</p> <p>Background</p> <p>Zerumbone, a sesquiterpene compound isolated from subtropical ginger, <it>Zingiber zerumbet</it> Smith, has been documented to exert antitumoral and anti- inflammatory activities. In this study, we demonstrate that zerumb...

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Bibliographic Details
Main Authors: Weng Hsing-Yu, Hsu Ming-Jen, Wang Ching-Chung, Chen Bing-Chang, Hong Chuang-Ye, Chen Mei-Chieh, Chiu Wen-Ta, Lin Chien-Huang
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Journal of Biomedical Science
Subjects:
Zerumbone
IKK
Akt
FOXO1
Glioblastoma multiforme
Online Access:http://www.jbiomedsci.com/content/19/1/86

Internet

http://www.jbiomedsci.com/content/19/1/86

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