Pericyte‐secreted IGF2 promotes breast cancer brain metastasis formation

Pericyte‐secreted IGF2 promotes breast cancer brain metastasis formation

Brain metastases are life‐threatening complications of triple‐negative breast cancer, melanoma, and a few other tumor types. Poor outcome of cerebral secondary tumors largely depends on the microenvironment formed by cells of the neurovascular unit, among which pericytes are the least characterized....

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Bibliographic Details
Main Authors: Kinga Molnár, Ádám Mészáros, Csilla Fazakas, Mihály Kozma, Fanni Győri, Zita Reisz, László Tiszlavicz, Attila E. Farkas, Ádám Nyúl‐Tóth, János Haskó, István A. Krizbai, Imola Wilhelm
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Molecular Oncology
Subjects:
brain metastasis
cerebral pericyte
insulin‐like growth factor 2
picropodophyllin
triple‐negative breast cancer
Online Access:https://doi.org/10.1002/1878-0261.12752

Internet

https://doi.org/10.1002/1878-0261.12752

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