MiR-155 induction by microbes/microbial ligands requires NF-kB-dependent de novo protein synthesis

MiR-155 induction by microbes/microbial ligands requires NF-kB-dependent de novo protein synthesis

MiR-155 regulates numerous aspects of innate and adaptive immune function. This miR is induced in response to toll-like receptor ligands, cytokines, and microbial infection. We have previously shown that miR-155 is induced in monocytes/macrophages infected with Francisella tularensis and suppresses...

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Bibliographic Details
Main Authors: Susheela eTridandapani, Thomas John Cremer, Kavin eFatehchand, Prexy eShah, Devyn eGillette, Hemal ePatel, Rachel L Marsh, Beth Y Besecker, Murugesan VS Rajaram, Thirumala-Devi eKanneganti, Larry eSchlesinger, Jonathan P Butchar
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Bacteria
Burkholderia
Infection
Mycobacterium
microRNA
TLR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00073/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00073/full

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