Evidence for a role of phenotypic mutations in virus adaptation

Summary: Viruses interact extensively with the host molecular machinery, but the underlying mechanisms are poorly understood. Bacteriophage T7 recruits the small protein thioredoxin of the Escherichia coli host as an essential processivity factor for the viral DNA polymerase. We challenged the phage...

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Bibliographic Details
Main Authors: Raquel Luzon-Hidalgo, Valeria A. Risso, Asuncion Delgado, Eduardo Andrés-León, Beatriz Ibarra-Molero, Jose M. Sanchez-Ruiz
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100225X