Simple water‐based tacrolimus enemas for refractory proctitis

Background and Aims Rectal ulcerative colitis (UC) and Crohn's disease (CD) often do not respond to conventional therapies. Oral and suppository tacrolimus are effective but often poorly tolerated or are complex to formulate. Tacrolimus is topically active, water soluble, and has minimal system...

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Bibliographic Details
Main Authors: Sasha R. Fehily, Felicity C. Martin, Michael A. Kamm
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:JGH Open
Subjects:
Online Access:https://doi.org/10.1002/jgh3.12280