Protocol for interfering peptide injection into adult mouse hippocampus and spatial memory testing

Summary: Metabotropic glutamate receptor-dependent long-term depression (mGluR-LTD) occurs in diverse brain regions and contributes to the plasticity of behavior, learning, and memory. mGluR-LTD relies on rapid (in minutes) local protein synthesis. Here, we describe a detailed protocol for deliverin...

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Bibliographic Details
Main Authors: Shanshan Cheng, Yuqian Shen, Zi Chao Zhang, Junhai Han
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721003865