Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3'-end antisense transcription.

Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3'-end antisense transcription.

Histone H3 di- and trimethylation on lysine 4 are major chromatin marks that correlate with active transcription. The influence of these modifications on transcription itself is, however, poorly understood. We have investigated the roles of H3K4 methylation in Saccharomyces cerevisiae by determining...

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Bibliographic Details
Main Authors: Thanasis Margaritis, Vincent Oreal, Nathalie Brabers, Laetitia Maestroni, Adeline Vitaliano-Prunier, Joris J Benschop, Sander van Hooff, Dik van Leenen, Catherine Dargemont, Vincent Géli, Frank C P Holstege
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3447963?pdf=render

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http://europepmc.org/articles/PMC3447963?pdf=render

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