A randomized controlled phase IIb trial of antigen-antibody immunogenic complex therapeutic vaccine in chronic hepatitis B patients.

A randomized controlled phase IIb trial of antigen-antibody immunogenic complex therapeutic vaccine in chronic hepatitis B patients.

BACKGROUND: The safety of the immune complexes composed of yeast-derived hepatitis B surface antigen (HBsAg) and antibodies (abbreviated as YIC) among healthy adults and chronic hepatitis B patients has been proved in phase I and phase IIa trial. A larger number of patients for study of dosage and e...

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Bibliographic Details
Main Authors: Dao-Zhen Xu, Kai Zhao, Li-Min Guo, Lan-Juan Li, Qing Xie, Hong Ren, Ji-Ming Zhang, Min Xu, Hui-Fen Wang, Wen-Xiang Huang, Xue-Fan Bai, Jun-Qi Niu, Pei Liu, Xin-Yue Chen, Xin-Liang Shen, Zheng-Hong Yuan, Xuan-Yi Wang, Yu-Mei Wen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2430617?pdf=render

Internet

http://europepmc.org/articles/PMC2430617?pdf=render

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