Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans

Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans

Inappropriate activation of innate immune responses in intestinal epithelial cells underlies the pathophysiology of inflammatory disorders of the intestine. Here we examine the physiological effects of immune hyperactivation in the intestine of the nematode Caenorhabditis elegans. We previously iden...

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Bibliographic Details
Main Authors: Hilary K. Cheesman, Rhonda L. Feinbaum, Jose Thekkiniath, Robert H. Dowen, Annie L. Conery, Read Pukkila-Worley
Format: Article
Language:English
Published: Oxford University Press 2016-03-01
Series:G3: Genes, Genomes, Genetics
Subjects:
innate immunity
immune regulation
C. elegans genetics
host-pathogen interactions
genetics of immunity
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.115.025650

Internet

http://g3journal.org/lookup/doi/10.1534/g3.115.025650

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