Chromosomal Islands of Streptococcus pyogenes and related streptococci: Molecular Switches for Survival and Virulence

Streptococcus pyogenes is a significant pathogen of humans, annually causing over 700,000,000 infections and 500,000 deaths. Virulence in S. pyogenes is closely linked to mobile genetic elements like phages and chromosomal islands (CI). S. pyogenes phage-like chromosomal islands (SpyCI) confer a co...

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Bibliographic Details
Main Authors: Scott Van Nguyen, William Michael Mcshan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00109/full