Alterations in the Antioxidant Enzyme Activities in the Neurodevelopmental Rat Model of Schizophrenia Induced by Glutathione Deficiency during Early Postnatal Life

Alterations in the Antioxidant Enzyme Activities in the Neurodevelopmental Rat Model of Schizophrenia Induced by Glutathione Deficiency during Early Postnatal Life

The aim of the present study was to assess the effects of L-buthionine-(S,R)-sulfoximine (BSO), a glutathione (GSH) synthesis inhibitor, and GBR 12909, a dopamine reuptake inhibitor, administered alone or in combination to Sprague-Dawley rats during early postnatal development (p5–p16), on the level...

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Bibliographic Details
Main Authors: Magdalena Górny, Anna Bilska-Wilkosz, Małgorzata Iciek, Marta Hereta, Kinga Kamińska, Adrianna Kamińska, Grażyna Chwatko, Zofia Rogóż, Elżbieta Lorenc-Koci
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Antioxidants
Subjects:
neurodevelopmental model of schizophrenia
GSH deficiency
antioxidant enzymes activity
ROS level
Online Access:https://www.mdpi.com/2076-3921/9/6/538

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https://www.mdpi.com/2076-3921/9/6/538

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