Small molecules promote CRISPR-Cpf1-mediated genome editing in human pluripotent stem cells

Small molecules promote CRISPR-Cpf1-mediated genome editing in human pluripotent stem cells

Precise genome editing in human pluripotent stem cells requires the development of methods for rapid and efficient genetic manipulation. Here, the authors screen for small molecules that enhance CRISPR-Cpf1-mediated genome engineering.

Bibliographic Details
Main Authors: Xiaojie Ma, Xi Chen, Yan Jin, Wenyan Ge, Weiyun Wang, Linghao Kong, Junfang Ji, Xing Guo, Jun Huang, Xin-Hua Feng, Junfen Fu, Saiyong Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03760-5

Internet

https://doi.org/10.1038/s41467-018-03760-5

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