IL-1 Receptor-associated kinase signaling and its role in inflammation, cancer progression and therapy resistance

IL-1 Receptor-associated kinase signaling and its role in inflammation, cancer progression and therapy resistance

Chronic inflammation has long been associated with the development of cancer. Amongst the various signaling pathways within cancer cells that can incite the expression of inflammatory molecules are those that activate IL-1 receptor associated kinases (IRAK). The IRAK family comprises of four family...

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Bibliographic Details
Main Authors: Ajay eJain, Sabina eKaczanowska, Eduardo eDavila
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Immunology
Subjects:
Inflammation
Therapeutics
Cancer
TLRs (Toll-like receptors)
IRAK-4
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00553/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00553/full

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