Estradiol Replacement Improves High-Fat Diet-Induced Obesity by Suppressing the Action of Ghrelin in Ovariectomized Rats

Estradiol Replacement Improves High-Fat Diet-Induced Obesity by Suppressing the Action of Ghrelin in Ovariectomized Rats

This study aims to investigate the effects of estradiol replacement on the orexigenic action of ghrelin in ovariectomized (OVX) obese rats fed with a high-fat diet (HFD). Four weeks after OVX at 9 weeks of age, Wistar rats were subcutaneously implanted with either 17β-estradiol (E2) or plac...

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Bibliographic Details
Main Authors: Naoko Yokota-Nakagi, Haruka Takahashi, Mizuho Kawakami, Akira Takamata, Yuki Uchida, Keiko Morimoto
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Nutrients
Subjects:
estradiol replacement
ghrelin
growth hormone secretagogue receptor
energy intake
high-fat diet-induced obesity
ovariectomized rat
Online Access:https://www.mdpi.com/2072-6643/12/4/907

Internet

https://www.mdpi.com/2072-6643/12/4/907

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