Afatinib for Advanced Non-small Cell Lung Cancer in a Case With an Uncommon Epidermal Growth Factor Receptor Mutation (G719A) Identified in the Cerebrospinal Fluid

Afatinib for Advanced Non-small Cell Lung Cancer in a Case With an Uncommon Epidermal Growth Factor Receptor Mutation (G719A) Identified in the Cerebrospinal Fluid

Few previous studies of patients with non-small cell lung cancer (NSCLC) and leptomeningeal metastases have used liquid biopsy of cerebrospinal fluid (CSF) to identify epidermal growth factor receptor (EGFR) mutations and guide therapy. A 34-year-old male patient with NSCLC and leptomeningeal metast...

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Bibliographic Details
Main Authors: Chunhua Ma, Chuoji Huang, Dongjiang Tang, Xin Ye, Zhi Li, Renzhong Liu, Ning Mu, Jing Li, Rong Jiang, Juncheng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
cerebrospinal fluid
G719A mutation
leptomeningeal metastases
NSCLC
afatinib
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00628/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00628/full

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