Statistical assessment of crosstalk enrichment between gene groups in biological networks.

MOTIVATION: Analyzing groups of functionally coupled genes or proteins in the context of global interaction networks has become an important aspect of bioinformatic investigations. Assessing the statistical significance of crosstalk enrichment between or within groups of genes can be a valuable tool...

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Bibliographic Details
Main Authors: Theodore McCormack, Oliver Frings, Andrey Alexeyenko, Erik L L Sonnhammer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553069?pdf=render