Associations Between Glutathione-S-Transferase Genotypes and Bronchial Hyperreactivity Patients With Di-isocyanate Induced Asthma. A Follow-Up Study

Introduction: Di-isocyanates TDI (toluene di-isocyanate), MDI (diphenylmethane di-isocyanate), and HDI (hexamethylene di-isocyanate) are the most common chemicals causing occupational asthma. Di-isocyanate inhalation has been reported to induce oxidative stress via reactive oxygen and nitrogen speci...

Full description

Bibliographic Details
Main Authors: Jussi Leppilahti, Marja-Leena Majuri, Timo Sorsa, Ari Hirvonen, Päivi Piirilä
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00220/full