Cellular Models and Assays to Study NLRP3 Inflammasome Biology

The NLRP3 inflammasome is a multi-protein complex that initiates innate immunity responses when exposed to a wide range of stimuli, including pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs). Inflammasome activation leads to the release of the pro-infla...

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Bibliographic Details
Main Authors: Giovanni Zito, Marco Buscetta, Maura Cimino, Paola Dino, Fabio Bucchieri, Chiara Cipollina
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/12/4294