Effect of transcutaneous cervical vagus nerve stimulation on the pituitary adenylate cyclase-activating polypeptide (PACAP) response to stress: A randomized, sham controlled, double blind pilot study

Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide that plays a key role in the neurobiology of the stress response, and prior studies suggest that its function is dysregulated in post-traumatic stress disorder (PTSD). Transcutaneous cervical vagus nerve stimulation (tcVNS) act...

Full description

Bibliographic Details
Main Authors: Nil Z. Gurel, Yunshen Jiao, Matthew T. Wittbrodt, Yi-An Ko, Allison Hankus, Emily G. Driggers, Stacy L. Ladd, Lucy Shallenberger, Nancy Murrah, Minxuan Huang, Ammer Haffar, Mhmtjamil Alkhalaf, Oleksiy Levantsevych, Jonathon A. Nye, Viola Vaccarino, Amit J. Shah, Omer T. Inan, J. Douglas Bremner, Bradley D. Pearce
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Comprehensive Psychoneuroendocrinology
Online Access:http://www.sciencedirect.com/science/article/pii/S2666497620300126