Influenza Viral Vectors Expressing Two Kinds of HA Proteins as Bivalent Vaccine Against Highly Pathogenic Avian Influenza Viruses of Clade 2.3.4.4 H5 and H7N9

Influenza Viral Vectors Expressing Two Kinds of HA Proteins as Bivalent Vaccine Against Highly Pathogenic Avian Influenza Viruses of Clade 2.3.4.4 H5 and H7N9

The H5 and H7N9 subtypes of highly pathogenic avian influenza viruses (HPAIVs) in China pose a serious challenge to public health and the poultry industry. In this study, a replication competent recombinant influenza A virus of the Í5N1 subtype expressing the H7 HA1 protein from a tri-cistronic NS s...

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Bibliographic Details
Main Authors: Jinping Li, Guangyu Hou, Yan Wang, Suchun Wang, Cheng Peng, Xiaohui Yu, Wenming Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Microbiology
Subjects:
influenza virus vector
non-structural protein
bivalent vaccine
H5
H7N9
avian influenza virus
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00604/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00604/full

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