A Matter of the Heart: The African Clawed Frog Xenopus as a Model for Studying Vertebrate Cardiogenesis and Congenital Heart Defects

A Matter of the Heart: The African Clawed Frog Xenopus as a Model for Studying Vertebrate Cardiogenesis and Congenital Heart Defects

The African clawed frog, Xenopus, is a valuable non-mammalian model organism to investigate vertebrate heart development and to explore the underlying molecular mechanisms of human congenital heart defects (CHDs). In this review, we outline the similarities between Xenopus and mammalian cardiogenesi...

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Bibliographic Details
Main Authors: Annemarie Hempel, Michael Kühl
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Xenopus
heart development
congenital heart defects
morpholino
model organism
Online Access:http://www.mdpi.com/2308-3425/3/2/21

Internet

http://www.mdpi.com/2308-3425/3/2/21

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