The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress

The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress

Phosphoglycerate mutase family member 5 (PGAM5) is a mitochondrial protein phosphatase that has been reported to be involved in various stress responses from mitochondrial quality control to cell death. However, its roles in vivo are largely unknown. Here, we show that Pgam5-deficient mice are resis...

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Bibliographic Details
Main Authors: Shiori Sekine, Akari Yao, Kazuki Hattori, Sho Sugawara, Isao Naguro, Masato Koike, Yasuo Uchiyama, Kohsuke Takeda, Hidenori Ichijo
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:EBioMedicine
Subjects:
Mitochondria
Stress response
Metabolic stress
Obesity
FGF21
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416300275

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http://www.sciencedirect.com/science/article/pii/S2352396416300275

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