Alteration of sheep coat color pattern by disruption of ASIP gene via CRISPR Cas9

Alteration of sheep coat color pattern by disruption of ASIP gene via CRISPR Cas9

Abstract Coat color is an important characteristic and economic trait in domestic sheep. Aiming at alteration of Chinese merino sheep coat color by genome manipulation, we disrupted sheep agouti signaling protein gene by CRISPR/Cas9. A total of seven indels were identified in 5 of 6 born lambs. Each...

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Bibliographic Details
Main Authors: Xuemei Zhang, Wenrong Li, Chenxi Liu, Xinrong Peng, Jiapeng Lin, Sangang He, Xuejiao Li, Bing Han, Ning Zhang, Yangsheng Wu, Lei Chen, Liqin Wang, MaYila, Juncheng Huang, Mingjun Liu
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08636-0

Internet

https://doi.org/10.1038/s41598-017-08636-0

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