A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C.

Rabies, caused by RNA viruses in the Genus Lyssavirus, is the most fatal of all infectious diseases. This neglected zoonosis remains a major public health problem in developing countries, causing the death of an estimated 25,000-159,000 people each year, with more than half of them in children. The...

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Main Authors: Federico Napolitano, Rossella Merone, Adele Abbate, Virginia Ammendola, Emma Horncastle, Francesca Lanzaro, Marialuisa Esposito, Alessandra Maria Contino, Roberta Sbrocchi, Andrea Sommella, Joshua D Duncan, Jospeh Hinds, Richard A Urbanowicz, Armin Lahm, Stefano Colloca, Antonella Folgori, Jonathan K Ball, Alfredo Nicosia, Benjamin Wizel, Stefania Capone, Alessandra Vitelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008459