Advances in the Renin-Angiotensin-Aldosterone System: Relevance to Diabetic Nephropathy

Hypertension is now recognized as a key contributory factor to the development and progression of kidney disease in both type 1 and type 2 diabetes. The renin angiotensin system (RAS) and its effector molecule angiotensin II, in particular, have a range of hemodynamic and nonhemodynamic effects that...

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Bibliographic Details
Main Authors: Audrey Koitka, Christos Tikellis
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2008.69