Comparison of sequencing platforms for single nucleotide variant calls in a human sample.

Comparison of sequencing platforms for single nucleotide variant calls in a human sample.

Next-generation sequencings platforms coupled with advanced bioinformatic tools enable re-sequencing of the human genome at high-speed and large cost savings. We compare sequencing platforms from Roche/454(GS FLX), Illumina/HiSeq (HiSeq 2000), and Life Technologies/SOLiD (SOLiD 3 ECC) for their abil...

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Bibliographic Details
Main Authors: Aakrosh Ratan, Webb Miller, Joseph Guillory, Jeremy Stinson, Somasekar Seshagiri, Stephan C Schuster
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3566181?pdf=render

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http://europepmc.org/articles/PMC3566181?pdf=render

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