Combined inhibition of STAT and Notch signalling effectively suppresses tumourigenesis by inducing apoptosis and inhibiting proliferation, migration and invasion in glioblastoma cells

Combined inhibition of STAT and Notch signalling effectively suppresses tumourigenesis by inducing apoptosis and inhibiting proliferation, migration and invasion in glioblastoma cells

Glioblastoma multiforme (GBM) is the most aggressive primary brain cancer and this is due to cancer cells being apoptosis-resistant and having increased cell proliferation, migration, invasion, and angiogenesis properties. Previous studies have indicated both STAT and Notch pathways being important...

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Bibliographic Details
Main Authors: Israt Jahan Tulip, Sung-Ok Kim, Eun-Jung Kim, Jaebong Kim, Jae Yong Lee, Hyunggee Kim, Sung-Chan Kim
Format: Article
Language:English
Published: Taylor & Francis Group 2021-06-01
Series:Animal Cells and Systems
Subjects:
glioblastoma
stat signalling
jagged
notch signalling
Online Access:http://dx.doi.org/10.1080/19768354.2021.1942983

Internet

http://dx.doi.org/10.1080/19768354.2021.1942983

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