Development of peptide-based lineage-specific serology for chronic Chagas disease: geographical and clinical distribution of epitope recognition.

Development of peptide-based lineage-specific serology for chronic Chagas disease: geographical and clinical distribution of epitope recognition.

BACKGROUND: Chagas disease, caused by infection with the protozoan Trypanosoma cruzi, remains a serious public health issue in Latin America. Genetically diverse, the species is sub-divided into six lineages, known as TcI-TcVI, which have disparate geographical and ecological distributions. TcII, Tc...

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Main Authors: Tapan Bhattacharyya, Andrew K Falconar, Alejandro O Luquetti, Jaime A Costales, Mario J Grijalva, Michael D Lewis, Louisa A Messenger, Trang T Tran, Juan-David Ramirez, Felipe Guhl, Hernan J Carrasco, Patricio Diosque, Lineth Garcia, Sergey V Litvinov, Michael A Miles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4031129?pdf=render

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http://europepmc.org/articles/PMC4031129?pdf=render

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