Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells.

While human mesenchymal stem cells (hMSCs), either in the bone marrow or in tumour microenvironment could be targeted by radiotherapy, their response is poorly understood. The oxic effects on radiosensitivity, cell cycle progression are largely unknown, and the radiation effects on hMSCs differentia...

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Bibliographic Details
Main Authors: Séverine Cruet-Hennequart, Carole Drougard, Georgina Shaw, Florence Legendre, Magali Demoor, Frank Barry, Jean-Louis Lefaix, Philippe Galéra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4383487?pdf=render